One of plants commonly used by the community for herbal medicine is betel (Piper betle Linn). The reason is that betel contains antiseptic substances that can kill germs. Betel nutritious overcome infection caused by bacteria and fungi. One of fungi that infects humans is Candida albicans. This study was conducted to find out the effectiveness of some concentration of inhibitory power of green leaf infusion to the growth of Candida albicans. The experiment was conducted between May and August 2017 at laboratory Centre of Poltekkes Kemenkes in Medan, Indonesia. Different concentrations were made with 7 types of boiling water of green betel leaves using sizes of 0.6, 1.0, 1.4, 1.8, 2.2, 2.6 and 3 g. Furthermore, various concentrations of green betel infuse were installed by using the diffusion disc method. One way anova was employed for analysing normal distributed data and post-hoc test was also used to determine the difference of inhibitory power for each concentration. Results show that infusion of betel leaf from various concentrations proved in inhibiting the growth of Candida albicans with p = 0.00 (<0.05). The mean of inhibitory zone values of each concentration were 12.10 (0.6), 14.10 (1.0), 15.80 (1.4), 17.40 (1.8), 20.40 (2.2), 22.50 (2.6) and 24.50 mm (3.0 g). While, the drag zone on positive control with ketoconazole were at 36.20 mm. This study also explain that the more number of leaves used in the manufacture of infuse, the more width of the inhibitory zone to Candida albicans growth. The results on post-hoc test show that there is no different inhibitory effect of each green betel infusion concentration to the growth of Candida albicans with p = 0.00 (<0.05).

Renal cell carcinoma is currently a tumor with an increasing incidence, associated with a higher mortality rate with an equal proportion for both sexes. After 59 years of age, there is an increased risk of kidney cancer as the incidence increases with age. In most cases renal cell carcinoma is discovered incidentally by independent imaging findings in renal pathology and in symptomatic cases the clinical triad consisting of macroscopic hematuria, lumbar fossa pain and presence of palpable mass. Renal clear cell carcinoma was the most frequent histological type with a grade 2 Fuhrman present in the majority of cases. It has been shown that renal tumors can infiltrate the renal capsule, perirenal fat, Gerotaös fascia, renal sinus, renal vein, vena cava and the lymphovascular system. The presence of tumor necrosis is associated with a poor prognosis in patients with renal masses >7cm. The mean tumor size was 7.17 (2-20) cm. The lymph node metastasis is very frequent, being the liver, lungs and bones the anatomical areas more prone to metastasize. The majority of patients diagnosed are in stage 1 and 3. The degree of surgical complexity and the surgical procedure indicate that there is no correlation (p = 0.00) between the imaging report and the surgical evaluation.